Mechanical evaluation of electrospun poly(ε-caprolactone) single fibers
نویسندگان
چکیده
منابع مشابه
Controlled biomineralization of electrospun poly(ε-caprolactone) fibers to enhance their mechanical properties.
Electrospun polymeric fibers have been investigated as scaffolding materials for bone tissue engineering. However, their mechanical properties, and in particular stiffness and ultimate tensile strength, cannot match those of natural bones. The objective of the study was to develop novel composite nanofiber scaffolds by attaching minerals to polymeric fibers using an adhesive material - the muss...
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We used a combined atomic force microscopic (AFM)/fluorescence microscopic technique to study the mechanical properties of individual, electrospun fibrinogen fibers in aqueous buffer. Fibers (average diameter 208 nm) were suspended over 12 microm-wide grooves in a striated, transparent substrate. The AFM, situated above the sample, was used to laterally stretch the fibers and to measure the app...
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Proof of the concept has been established through series of electrospinning experiments with different PEO and block copolymer concentrations. An increase of the surface peptide functional groups characterized by X-ray Photoelectron Spectroscopy (XPS) indicates 5~10 times aggregation of the block copolymer on the surface of the electrospun fibers. By varying the PEO and BCP concentrations, cond...
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SUMMARY BACKGROUND Blood clots perform the mechanical task of stemming the flow of blood. OBJECTIVES To advance understanding and realistic modeling of blood clot behavior we determined the mechanical properties of the major structural component of blood clots, fibrin fibers. METHODS We used a combined atomic force microscopy (AFM)/fluorescence microscopy technique to determine key mechanic...
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A promising therapy for retinal diseases is to employ biodegradable scaffolds to deliver retinal progenitor cells (RPCs) for repairing damaged or diseased retinal tissue. In the present study, cationic chitosan-graft-poly(ɛ-caprolactone)/polycaprolactone (CS-PCL/PCL) hybrid scaffolds were successfully prepared by electrospinning. Characterization of the obtained nanofibrous scaffolds indicated ...
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ژورنال
عنوان ژورنال: Materials Today Communications
سال: 2020
ISSN: 2352-4928
DOI: 10.1016/j.mtcomm.2020.101211